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Livres
Articles (74)
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Investigating the effects of nintedanib on biomarkers of extracellular matrix turnover in patients with IPF: design of the randomised placebo-controlled INMARK®trial

Maher, Toby M, Stowasser, Susanne, Nishioka, Yasuhiko, White, Eric S, Cottin, Vincent, Noth, Imre, Selman, Moisés, Blahova, Zuzana, Wachtlin, Daniel, Diefenbach, Claudia, Jenkins, R Gisli

Journal:

BMJ Open Respiratory Research

Année:

2018

Langue:

english

Fichier:

PDF, 546 KB

english, 2018

The first thoracic triumvirate

Hart, Nicholas, Jenkins, Gisli, Smyth, Alan

Journal:

Thorax

Année:

2015

Langue:

english

Fichier:

PDF, 326 KB

english, 2015

To Suppress the Radicals We Must Have Biomarkers of Oxidative Stress

Jenkins, R. Gisli

Journal:

American Journal of Respiratory and Critical Care Medicine

Année:

2016

Langue:

english

Fichier:

PDF, 439 KB

english, 2016

Time for a change: is idiopathic pulmonary fibrosis still idiopathic and only fibrotic?

Wolters, Paul J, Blackwell, Timothy S, Eickelberg, Oliver, Loyd, James E, Kaminski, Naftali, Jenkins, Gisli, Maher, Toby M, Molina-Molina, Maria, Noble, Paul W, Raghu, Ganesh, Richeldi, Luca, Schwarz,

Journal:

The Lancet Respiratory Medicine

Année:

2018

Langue:

english

Fichier:

PDF, 169 KB

english, 2018

Novel idiopathic pulmonary fibrosis susceptibility variants revealed by deep sequencing

Lorenzo-Salazar, Jose M., Ma, Shwu-Fan, Jou, Jonathan, Hou, Pei-Chi, Guillen-Guio, Beatriz, Allen, Richard J., Jenkins, R. Gisli, Wain, Louise V., Oldham, Justin M., Noth, Imre, Flores, Carlos

Journal:

ERJ Open Research

Année:

2019

Langue:

english

Fichier:

PDF, 661 KB

english, 2019

Review of the British Thoracic Society Winter Meeting 2018, 5–7 December 2018, London, UK

Goodwin, Amanda T, Singanayagam, Aran, Jenkins, Gisli

Journal:

Thorax

Année:

2019

Langue:

english

Fichier:

PDF, 311 KB

english, 2019

British Thoracic Society survey of rehabilitation to support recovery of the post-COVID-19 population

Singh, Sally J, Barradell, Amy C, Greening, Neil J, Bolton, Charlotte, Jenkins, Gisli, Preston, Louise, Hurst, John R

Journal:

BMJ Open

Année:

2020

Fichier:

PDF, 1.92 MB

2020

Efficient transfection of non-proliferating human airway epithelial cells with a synthetic vector system

Qing-Hai Meng, Danielle Robinson, R. Gisli Jenkins, Robin J. McAnulty, Stephen L. Hart

Journal:

The Journal of Gene Medicine

Année:

2004

Langue:

english

Fichier:

PDF, 386 KB

english, 2004

Tryptase activates TGFβ in human airway smooth muscle cells via direct proteolysis

Amanda L. Tatler, Joanne Porte, Alan Knox, Gisli Jenkins, Linhua Pang

Journal:

Biochemical and Biophysical Research Communications

Année:

2008

Langue:

english

Fichier:

PDF, 227 KB

english, 2008

The role of proteases in transforming growth factor-β activation

Gisli Jenkins

Journal:

The International Journal of Biochemistry & Cell Biology

Année:

2008

Langue:

english

Fichier:

PDF, 491 KB

english, 2008

Severity of Lung Injury in Cyclooxygenase-2-Deficient Mice Is Dependent on Reduced Prostaglandin E2 Production

Rebecca J. Hodges, R. Gisli Jenkins, Caroline P.D. Wheeler-Jones, Danielle M. Copeman, Stephen E. Bottoms, Geoffrey J. Bellingan, Carmel B. Nanthakumar, Geoffrey J. Laurent, Stephen L. Hart, Martyn L.

Journal:

The American Journal of Pathology

Année:

2004

Langue:

english

Fichier:

PDF, 1.46 MB

english, 2004

Cyclooxygenase-2 Deficiency Results in a Loss of the Anti-Proliferative Response to Transforming Growth Factor-β in Human Fibrotic Lung Fibroblasts and Promotes Bleomycin-Induced Pulmonary Fibrosis in Mice

Carmel B. Keerthisingam, R. Gisli Jenkins, Nicholas K. Harrison, Norma A. Hernandez-Rodriguez, Helen Booth, Geoffrey J. Laurent, Stephen L. Hart, Martyn L. Foster, Robin J. McAnulty

Journal:

The American Journal of Pathology

Année:

2001

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2001

Lysophosphatidic Acid Induces αvβ6 Integrin-Mediated TGF-β Activation via the LPA2 Receptor and the Small G Protein Gαq

Ming Yan Xu, Joanne Porte, Alan J. Knox, Paul H. Weinreb, Toby M. Maher, Shelia M. Violette, Robin J. McAnulty, Dean Sheppard, Gisli Jenkins

Journal:

The American Journal of Pathology

Année:

2009

Langue:

english

Fichier:

PDF, 2.22 MB

english, 2009

Role of integrin-mediated TGFβ activation in the pathogenesis of pulmonary fibrosis

Goodwin, Amanda, Jenkins, Gisli

Journal:

Biochemical Society Transactions

Année:

2009

Langue:

english

Fichier:

PDF, 295 KB

english, 2009

TGF-β Activation and Lung Fibrosis

Tatler, Amanda L., Jenkins, Gisli

Journal:

Proceedings of the American Thoracic Society

Année:

2012

Langue:

english

Fichier:

PDF, 435 KB

english, 2012

Assessment of the effect of potential antifibrotic compounds on total and αVβ6 integrin-mediated TGF-β activation

Porte, Joanne, Jenkins, Gisli

Journal:

Pharmacology Research & Perspectives

Année:

2014

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2014

Into the matrix

Sivakumar, Pitchumani, Ntolios, Paschalis, Jenkins, Gisli, Laurent, Geoffrey

Journal:

Current Opinion in Pulmonary Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 2.04 MB

english, 2012

Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study

Jenkins, R Gisli, Simpson, Juliet K, Saini, Gauri, Bentley, Jane H, Russell, Anne-Marie, Braybrooke, Rebecca, Molyneaux, Philip L, McKeever, Tricia M, Wells, Athol U, Flynn, Aiden, Hubbard, Richard B,

Journal:

The Lancet Respiratory Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 4.53 MB

english, 2015

Endotyping idiopathic pulmonary fibrosis should improve outcomes for all patients with progressive fibrotic lung disease

Jenkins, Gisli

Journal:

Thorax

Année:

2015

Langue:

english

Fichier:

PDF, 458 KB

english, 2015

Highlights from this issue

Hart, Nicholas, Jenkins, Gisli, Smyth, Alan

Journal:

Thorax

Année:

2015

Langue:

english

Fichier:

PDF, 426 KB

english, 2015

Stretch Induced Activation of TGF-β1 in Pulmonary Fibrosis

Froese, Aaron R, Shimbori, Chiko, Bellaye, Pierre-Simon, Ask, Kjetil, Inman, Mark, Obex, Steffen, Fatima, Safoora, Jenkins, Gisli, Gauldie, Jack, Kolb, Martin

Journal:

American Journal of Respiratory and Critical Care Medicine

Année:

2016

Langue:

english

Fichier:

PDF, 2.43 MB

english, 2016

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] B101. PATHOGENESIS OF ACUTE LUNG INJURY - The Effect Of Inhibiting Toll-Like Receptor 4 On The Development Of Bleomycin-Induced Acute Lung Injury

Habgood, Anthony, Tatler, Amanda L., John, Alison E., Elson, Greg, Jenkins, Gisli

Année:

2012

Langue:

english

Fichier:

PDF, 17 KB

english, 2012

Molecular Endotyping of Pulmonary Fibrosis

Goodwin, Amanda T., Jenkins, Gisli

Journal:

CHEST Journal

Année:

2016

Langue:

english

Fichier:

PDF, 392 KB

english, 2016

Cyclooxygenase-2 Overexpression, Using an Integrin-Targeted Gene Delivery System (the LID Vector), Inhibits Fibroblast Proliferation In Vitro and Leads to Increased Prostaglandin E2 in the Lung

Jenkins, Gisli, Hart, Stephen L., Hodges, Rebecca J., Meng, Qin-Hai, Kinnon, Christine, Laurent, Geoffrey J., McAnulty, Robin J.

Journal:

CHEST Journal

Année:

2002

Langue:

english

Fichier:

PDF, 208 KB

english, 2002

[American Thoracic Society American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado - ()] B64. PATHWAYS REGULATING FIBROBLAST GENE EXPRESSION - Increased MRNA Decay Is Involved In The Reduced Expression Of IP-10 In Idiopathic Pulmonary Fibrosis

Xu, Mingyan, Feghali-Bostwick, Carol A., Jenkins, Gisli, Knox, Alan, Pang, Linhua

Année:

2011

Langue:

english

Fichier:

PDF, 17 KB

english, 2011

Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary fibrosis

Habgood, Anthony N, Tatler, Amanda L, Porte, Joanne, Wahl, Sharon M, Laurent, Geoffrey J, John, Alison E, Johnson, Simon R, Jenkins, Gisli

Journal:

Laboratory Investigation

Année:

2016

Langue:

english

Fichier:

PDF, 2.11 MB

english, 2016

An American Thoracic Society Official Research Statement: Future Directions in Lung Fibrosis Research

White, Eric S., Borok, Zea, Brown, Kevin K., Eickelberg, Oliver, Guenther, Andreas, Jenkins, R. Gisli, Kolb, Martin, Martinez, Fernando J., Roman, Jesse, Sime, Patricia

Journal:

American Journal of Respiratory and Critical Care Medicine

Année:

2016

Langue:

english

Fichier:

PDF, 619 KB

english, 2016

Acute Exacerbation of Idiopathic Pulmonary Fibrosis: An International Working Group Report

Collard, Harold R, Ryerson, Christopher J, Corte, Tamera J, Jenkins, Gisli, Kondoh, Yasuhiro, Lederer, David J, Lee, Joyce S, Maher, Toby M, Wells, Athol U, Antoniou, Katerina M, Behr, Juergen, Brown,

Journal:

American Journal of Respiratory and Critical Care Medicine

Année:

2016

Langue:

english

Fichier:

PDF, 2.26 MB

english, 2016

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] B65. EPIGENETIC REGULATION OF LUNG CELL FUNCTION - Binding Of The Polycomb Protein Complex Via Histone Hypermethylation At Lysine 27 (H3K27me3) Is Involved In IP-10 Repression In Idiopathic Pulmonary Fibrosis (IPF)

Coward, William R., Feghali-Bostwick, Carol, Jenkins, Gisli, Knox, Alan J., Pang, Linhua

Année:

2012

Langue:

english

Fichier:

PDF, 19 KB

english, 2012

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] B28. EMERGING BIOMARKERS OF COMPLEX LUNG DISEASES - Increased Fibrocytes In Patients Newly Diagnosed With Idiopathic Pulmonary Fibrosis

Maharaj, Shyam S., Baroke, Eva, Tenuta, Alycia, Blanchard, Andy, Simpson, Juliet, Jenkins, Gisli, Braybrooke, Rebecca, Saini, Gauri, Bailey, Helen, Gauldie, Jack, Kolb, Martin R.J.

Année:

2012

Langue:

english

Fichier:

PDF, 18 KB

english, 2012

[American Thoracic Society American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California - ()] C103. PATHOGENESIS, BIOMARKERS, AND RISK FACTORS FOR INTERSTITIAL LUNG DISEASE: FROM BENCH TO BEDSIDE - The PROFILE Study: A Prospective Study Of Fibrosis In Lung Endpoints To Discover And Qualify Biomarkers For Use In Clinical Trials

Saini, Gauri, Jenkins, Gisli, Mckeever, Tricia, Simpson, Juliet, Hubbard, Richard, Johnson, Simon, Braybrooke, Rebecca, Russell, Anne-Marie, Meakin, Garry, Sweeney, Lisa, Bailey, Helen, Marshall, Rich

Année:

2012

Langue:

english

Fichier:

PDF, 19 KB

english, 2012

Investigating lung responses with functional hyperpolarized xenon-129 MRI in an ex vivo rat model of asthma

Lilburn, David M.L., Tatler, Amanda L., Six, Joseph S., Lesbats, Clémentine, Habgood, Anthony, Porte, Joanne, Hughes-Riley, Theodore, Shaw, Dominick E., Jenkins, Gisli, Meersmann, Thomas

Journal:

Magnetic Resonance in Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 6.10 MB

english, 2015

TNFα promotes CAR-dependent migration of leukocytes across epithelial monolayers

Morton, Penny E., Hicks, Alexander, Ortiz-Zapater, Elena, Raghavan, Swetavalli, Pike, Rosemary, Noble, Alistair, Woodfin, Abigail, Jenkins, Gisli, Rayner, Emma, Santis, George, Parsons, Maddy

Journal:

Scientific Reports

Année:

2016

Langue:

english

Fichier:

PDF, 1.80 MB

english, 2016

Study the past to divine the future. Confucius' wisdom doesn't work for idiopathic pulmonary fibrosis

Kolb, Martin, Jenkins, Gisli, Richeldi, Luca

Journal:

Thorax

Année:

2016

Langue:

english

Fichier:

PDF, 405 KB

english, 2016

Climate change and lung health: the challenge for a new president

Hopkinson, Nicholas S, Hart, Nicholas, Jenkins, Gisli, Kaminski, Naftali, Rosenfeld, Margaret, Smyth, Alan, Wilkinson, Alex

Journal:

Thorax

Année:

2017

Langue:

english

Fichier:

PDF, 118 KB

english, 2017

Highlights from this issue

Hart, Nicholas, Jenkins, Gisli, Smyth, Alan

Journal:

Thorax

Année:

2016

Langue:

english

Fichier:

PDF, 333 KB

english, 2016

First year of the thoracic triumvirate

Hart, Nicholas, Jenkins, Gisli, Smyth, Alan Robert

Journal:

Thorax

Année:

2016

Langue:

english

Fichier:

PDF, 333 KB

english, 2016

Highlights from this issue

Hart, Nicholas, Jenkins, Gisli, Smyth, Alan

Journal:

Thorax

Année:

2016

Langue:

english

Fichier:

PDF, 599 KB

english, 2016

An Official American Thoracic Society Workshop Report: Use of Animal Models for the Preclinical Assessment of Potential Therapies for Pulmonary Fibrosis

Jenkins, R. Gisli, Moore, Bethany B., Chambers, Rachel C., Eickelberg, Oliver, Königshoff, Melanie, Kolb, Martin, Laurent, Geoffrey J., Nanthakumar, Carmel B., Olman, Mitchell A., Pardo, Annie, Selman

Journal:

American Journal of Respiratory Cell and Molecular Biology

Année:

2017

Langue:

english

Fichier:

PDF, 676 KB

english, 2017

Review of the British Thoracic Society Winter Meeting 2016, 7–9 December, London, UK

Woodcock, Hannah V, José, Ricardo J, Jenkins, Gisli

Journal:

Thorax

Année:

2017

Langue:

english

Fichier:

PDF, 228 KB

english, 2017

Highlights from this issue

Hart, Nicholas, Jenkins, Gisli, Smyth, Alan

Journal:

Thorax

Année:

2016

Langue:

english

Fichier:

PDF, 353 KB

english, 2016

Highlights from this issue

Hart, Nicholas, Jenkins, Gisli, Smyth, Alan

Journal:

Thorax

Année:

2016

Langue:

english

Fichier:

PDF, 373 KB

english, 2016

Highlights from this issue:

Hart, Nicholas, Jenkins, Gisli, Smyth, Alan

Journal:

Thorax

Année:

2015

Langue:

english

Fichier:

PDF, 355 KB

english, 2015

IPF: Moving from Idiopathic to Infectious Pulmonary Fibrosis?

Jenkins, Gisli

Journal:

American Journal of Respiratory and Critical Care Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 442 KB

english, 2017

Caffeine inhibits TGFβ activation in epithelial cells, interrupts fibroblast responses to TGFβ, and reduces established fibrosis in ex vivo precision-cut lung slices

Tatler, Amanda L, Barnes, Josephine, Habgood, Anthony, Goodwin, Amanda, McAnulty, Robin J, Jenkins, Gisli

Journal:

Thorax

Année:

2016

Langue:

english

Fichier:

PDF, 765 KB

english, 2016

ECM Crosslinking Enhances Fibroblast Growth and Protects Against Matrix Proteolysis in Lung Fibrosis

Philp, Christopher J, Siebeke, Ivonne, Clements, Debbie, Miller, Suzanne, Habgood, Anthony, John, Alison E, Navaratnam, Vidya, Hubbard, Richard B., Jenkins, Gisli, Johnson, Simon R

Journal:

American Journal of Respiratory Cell and Molecular Biology

Année:

2017

Langue:

english

Fichier:

PDF, 14.88 MB

english, 2017

Interplay Between EZH2 and G9a Regulates CXCL10 Gene Repression in Idiopathic Pulmonary Fibrosis

Coward, William R, Brand, Oliver J, Pasini, Alice, Jenkins, Gisli, Knox, Alan J, Pang, Linhua

Journal:

American Journal of Respiratory Cell and Molecular Biology

Année:

2017

Langue:

english

Fichier:

PDF, 1.63 MB

english, 2017

Highlights from this issue

Hart, Nicholas, Jenkins, Gisli, Smyth, Alan

Journal:

Thorax

Année:

2016

Langue:

english

Fichier:

PDF, 375 KB

english, 2016

A big beautiful wall against infection

Jenkins, Gisli

Journal:

Thorax

Année:

2017

Langue:

english

Fichier:

PDF, 446 KB

english, 2017

Embracing social media: Table 1

Hopkinson, Nicholas S, Hart, Nicholas, Jenkins, Gisli, Smyth, Alan

Journal:

Thorax

Année:

2015

Langue:

english

Fichier:

PDF, 337 KB

english, 2015